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CHI - GSP

$96 Find cheap flights from Chicago to Greenville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Greenville departing on 7/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/15
Sat 6/22

Search hundreds of travel sites at once for deals on flights to Greenville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Greenville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Chicago to Greenville, as well as popular online travel agencies
In the last 7 days travelers have searched 42,211,976 times on KAYAK, and here is why:

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Bundle and saveSave money when you bundle your flight + hotel.

Cheap flight deals from Chicago to Greenville (CHI-GSP)

 
These are the cheapest deals for flights from Chicago to Greenville currently on KAYAK along with options from the most popular airlines KAYAK users selected for this route. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Chicago to Greenville

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Chicago to Greenville.

Recent one-way flight deals from Chicago to Greenville

Only flying one-way? Below are some of the best one-way flight deals from Chicago to Greenville found on KAYAK recently.

Recent last minute flight deals from Chicago to Greenville

Leaving soon but still want a bargain? Check out these latest deals for last minute flights from Chicago to Greenville.

Recent direct flight deals from Chicago to Greenville

The latest deals for direct flights from Chicago to Greenville so you can sit back and relax without the need for a layover.

Cheap bus & train deals from Chicago to Greenville

Find recent round-trip train or bus tickets from Chicago to Greenville.

All round-trip flight deals to Greenville

The cheapest plane tickets to Greenville found on KAYAK recently.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
6:50 pm - 11:56 pmMDW-GSP
4h 06m1 stop
6:30 pm - 9:47 pmGSP-MDW
4h 17m1 stop
$268Delta
Find Deal
Tue, Aug 20 - Sat, Aug 24
5:30 am - 12:12 pmORD-GSP
5h 42m1 stop
12:52 pm - 4:05 pmGSP-ORD
4h 13m1 stop
$275American Airlines
Find Deal
Mon, Jul 1 - Thu, Jul 4
5:28 am - 10:50 amORD-GSP
4h 22m1 stop
7:40 am - 8:49 amGSP-ORD
2h 09mnonstop
$277American Airlines
Find Deal
Tue, Jul 16 - Tue, Jul 23
2:20 pm - 5:17 pmORD-GSP
1h 57mnonstop
7:59 am - 9:04 amGSP-ORD
2h 05mnonstop
$279American Airlines
Find Deal
Thu, Aug 1 - Wed, Aug 7
1:40 pm - 6:04 pmORD-GSP
3h 24m1 stop
7:30 pm - 11:58 pmGSP-ORD
5h 28m1 stop
$280American Airlines
Find Deal
Fri, May 31 - Wed, Jun 12
12:15 pm - 6:04 pmORD-GSP
4h 49m1 stop
7:30 pm - 11:58 pmGSP-ORD
5h 28m1 stop
$282American Airlines
Find Deal
Fri, May 31 - Wed, Jun 12
6:00 am - 10:52 amORD-GSP
3h 52m1 stop
4:00 pm - 9:38 pmGSP-ORD
6h 38m1 stop
$288Delta
Find Deal
Wed, Jun 12 - Wed, Jun 12
4:35 pm - 11:44 pmORD-GSP
6h 09m1 stop
5:57 pm - 11:50 amGSP-ORD
18h 53m2 stops
$421United Airlines
Find Deal
Tue, Jul 16 - Tue, Jul 23
7:50 pm - 10:50 pmORD-GSP
2h 00mnonstop
6:00 am - 7:08 amGSP-ORD
2h 08mnonstop
$479United Airlines
Find Deal
Sat, May 25 - Sat, Jul 20
9:46 am - 12:03 pmMDW-GSP
25h 17m3 stops
6:08 pm - 11:27 amGSP-MDW
18h 19m3 stops
$1,102WestJet
Find Deal
Fri, May 31 - Fri, Jun 7
6:43 pm - 10:52 amORD-GSP
15h 09m1 stop
Tue, Jul 23
9:36 am - 10:52 amORD-GSP
24h 16m2 stops
Tue, Jul 23
5:05 am - 2:57 pmORD-GSP
8h 52m1 stop
Mon, Jun 10
8:19 am - 11:09 amORD-GSP
1h 50mnonstop
$130American Airlines
Find Deal
Thu, May 30
3:20 pm - 7:44 pmORD-GSP
3h 24m1 stop
$138American Airlines
Find Deal
Thu, May 30
6:00 am - 10:56 amMDW-GSP
3h 56m1 stop
$139Delta
Find Deal
Thu, May 30
6:55 pm - 11:55 pmMDW-GSP
4h 00m1 stop
$144Delta
Find Deal
Tue, Jul 23
7:12 am - 10:12 amORD-GSP
2h 00mnonstop
$165United Airlines
Find Deal
Thu, May 30
9:08 pm - 4:58 pmMDW-GSP
18h 50m2 stops
$172Allegiant Air
Find Deal
Mon, Jun 24
6:13 pm - 9:13 pmORD-GSP
2h 00mnonstop
$190United Airlines
Find Deal
Mon, Jun 10
6:48 pm - 11:57 pmMDW-GSP
4h 09m1 stop
5:15 pm - 10:01 pmGSP-MDW
5h 46m1 stop
$548Delta
Find Deal
Fri, May 17 - Tue, May 21
5:57 pm - 11:57 pmORD-GSP
5h 00m1 stop
3:23 pm - 9:26 pmGSP-ORD
7h 03m1 stop
$548Delta
Find Deal
Fri, May 17 - Tue, May 21
5:23 pm - 11:11 pmORD-GSP
4h 48m1 stop
6:09 am - 9:20 amGSP-ORD
4h 11m1 stop
$568Delta
Find Deal
Fri, May 17 - Sun, May 19
8:19 am - 11:09 amORD-GSP
1h 50mnonstop
8:10 am - 9:15 amGSP-ORD
2h 05mnonstop
$620American Airlines
Find Deal
Mon, May 20 - Tue, May 21
7:25 pm - 10:09 pmORD-GSP
1h 44mnonstop
6:00 am - 8:56 amGSP-ORD
3h 56m1 stop
$628American Airlines
Find Deal
Mon, May 20 - Tue, May 21
7:30 am - 12:12 pmORD-GSP
3h 42m1 stop
5:00 am - 8:56 amGSP-ORD
4h 56m1 stop
$636American Airlines
Find Deal
Mon, May 20 - Tue, May 21
5:47 pm - 11:11 pmMDW-GSP
4h 24m1 stop
6:09 am - 9:06 amGSP-MDW
3h 57m1 stop
$639Delta
Find Deal
Fri, May 17 - Thu, May 23
7:10 am - 10:08 amORD-GSP
1h 58mnonstop
5:35 pm - 6:50 pmGSP-ORD
2h 15mnonstop
$778United Airlines
Find Deal
Fri, May 17 - Fri, May 17
1:04 pm - 9:14 pmORD-GSP
7h 10m1 stop
12:53 pm - 7:25 amGSP-ORD
19h 32m2 stops
$900United Airlines
Find Deal
Fri, May 17 - Sat, May 18
5:00 pm - 11:28 amMDW-GSP
17h 28m3 stops
10:43 am - 6:07 pmGSP-MDW
32h 24m3 stops
$1,466WestJet
Find Deal
Sat, May 18 - Tue, May 21
2:20 pm - 5:17 pmORD-GSP
1h 57mnonstop
7:59 am - 9:04 amGSP-ORD
2h 05mnonstop
$279American Airlines
Find Deal
Thu, Aug 1 - Wed, Aug 7
6:43 pm - 9:47 pmORD-GSP
2h 04mnonstop
5:50 pm - 7:00 pmGSP-ORD
2h 10mnonstop
$284American Airlines
Find Deal
Wed, Jul 3 - Sat, Jul 6
6:43 pm - 9:47 pmORD-GSP
2h 04mnonstop
5:50 pm - 7:00 pmGSP-ORD
2h 10mnonstop
$286American Airlines
Find Deal
Mon, Jul 1 - Sat, Jul 13
6:43 pm - 9:47 pmORD-GSP
2h 04mnonstop
7:15 am - 8:20 amGSP-ORD
2h 05mnonstop
$289American Airlines
Find Deal
Wed, Jun 26 - Sun, Jun 30
2:28 pm - 5:22 pmORD-GSP
1h 54mnonstop
7:15 am - 8:20 amGSP-ORD
2h 05mnonstop
$300American Airlines
Find Deal
Thu, Jun 6 - Tue, Jun 11
6:43 pm - 9:47 pmORD-GSP
2h 04mnonstop
5:52 pm - 6:56 pmGSP-ORD
2h 04mnonstop
$309American Airlines
Find Deal
Sat, Jun 8 - Mon, Jun 10
2:28 pm - 5:22 pmORD-GSP
1h 54mnonstop
7:15 am - 8:20 amGSP-ORD
2h 05mnonstop
$316American Airlines
Find Deal
Fri, Jun 14 - Fri, Jun 21
6:43 pm - 9:47 pmORD-GSP
2h 04mnonstop
7:15 am - 8:20 amGSP-ORD
2h 05mnonstop
$324American Airlines
Find Deal
Thu, Jun 6 - Tue, Jun 11
7:12 am - 10:12 amORD-GSP
2h 00mnonstop
5:45 pm - 6:55 pmGSP-ORD
2h 10mnonstop
$354United Airlines
Find Deal
Thu, May 30 - Sat, Jun 1
7:50 pm - 10:50 pmORD-GSP
2h 00mnonstop
6:00 am - 7:08 amGSP-ORD
2h 08mnonstop
$479United Airlines
Find Deal
Sat, May 25 - Sat, Jul 20

Flights from Chicago to Greenville - Travel Insights & Trends

Get data-powered insights and trends into flights from Chicago to Greenville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago to Greenville flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for one-way flights from Chicago to Greenville.
Our data shows that the cheapest route for a one-way flight from Chicago to Greenville cost $154 and was between Chicago O'Hare Intl Airport and Greenville. On average, the best prices are found if you fly this route. The average price for a return flight for this route is $273.

What’s the cheapest day of the week to fly from Chicago to Greenville?

The average price of all flights from Chicago to Greenville clicked on KAYAK for each day over the last 12 months.
If your flying dates are flexible, you should consider flying to Greenville on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Chicago to Greenville. For your return ticket, we recommend flying on a Saturday and avoiding Sundays for the best deals.

What is the cheapest month to fly from Chicago to Greenville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Chicago to Greenville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Chicago to Greenville is January, where tickets cost $258 on average. On the other hand, the most expensive months are March and April, where the average cost of tickets is $391 and $354 respectively.

How far in advance should I book a flight from Chicago to Greenville?

To calculate daily average prices, KAYAK takes all prices for each day before departure over the last year for flights from Chicago to Greenville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each month.
To get a below average price on the flight from Chicago to Greenville, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 70 days before departure.

Which airlines provide the cheapest flights from Chicago to Greenville?

The cheapest price for the route for each airline clicked by KAYAK users in the last 72 hours.
The cheapest return flight ticket from Chicago to Greenville found by KAYAK users in the last 72 hours was for $268 on Delta, followed by American Airlines ($275). One-way flight deals have also been found from as low as $130 on American Airlines and from $139 on Delta.

Which airlines fly non-stop between Chicago and Greenville?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for flights from Chicago to Greenville.
There are 2 airlines that fly nonstop from Chicago to Greenville. They are American Airlines and United Airlines. The cheapest airline for this route is United Airlines, with the best one-way deal found costing $168. On average, the best prices for this route can be found at American Airlines.

How many flights are there between Chicago and Greenville per day?

Each day, there are between 4 and 7 nonstop flights that take off from Chicago and land in Greenville, with an average flight time of 1h 57m. The most common departure time is 6:00 pm and most flights take off in the evening. Each week, there are 38 flights. The most frequent day of departure is Monday, when 18% of all weekly flights depart. The fewest flights depart on a Tuesday.

Which cabin class options are there for flights between Chicago and Greenville?

The average price of flights for each cabin class for the route found by users searching on KAYAK over the last 2 weeks.
There are 3 cabin class options for the route. These are First, Business and Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

How long does a flight from Chicago to Greenville take?

The duration of a nonstop flight to Greenville from Chicago is typically 1h 44m. The journey crosses a distance of 564 miles.

What’s the earliest departure time from Chicago to Greenville?

Early birds can take the earliest flight from Chicago at 7:12 am and will be landing in Greenville at 10:12 am.

What’s the latest departure time from Chicago to Greenville?

If you prefer to fly at night, the latest flight from Chicago to Greenville jets off at 7:50 pm and lands at 10:50 pm.

Good to know

Low season

January

High season

July

Cheapest flight

$96
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Chicago O'Hare Airport to Greenville

When to book flights from Chicago to Greenville

Are your dates flexible? Find out the best times to travel from Chicago to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Chicago to Greenville

  • What is the cheapest flight from Chicago to Greenville?

    In the last 3 days, the lowest price for a flight from Chicago to Greenville was $96 for a one-way ticket and $268 for a round-trip.

  • Do I need a passport to fly between Chicago and Greenville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Chicago to Greenville?

    When flying out of Chicago you will be using one of these airports: Chicago Midway or Chicago O'Hare Intl. You will be landing at Greenville.

  • Which airlines offer Wi-Fi service onboard planes from Chicago to Greenville?

    Only American Airlines offers inflight Wi-Fi service on the Chicago to Greenville flight route.

  • Which aircraft models fly most regularly from Chicago to Greenville?

    The Embraer 175 (Enhanced Winglets) is the aircraft model that flies most regularly on the Chicago to Greenville flight route.

  • Which airline alliances offer flights from Chicago to Greenville?

    oneworld, and Star Alliance are the airline alliances operating flights between Chicago and Greenville, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Chicago to Greenville?

    There are nonstop flights from Chicago to Greenville on a daily basis.

  • Which is the best airline for flights from Chicago to Greenville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Chicago to Greenville are Delta and United Airlines. With an average price for the route of $282 and an overall rating of 8.0, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $323 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Chicago to Greenville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Greenville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Greenville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Greenville from Chicago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Greenville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Greenville with an airline and back to Chicago with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Greenville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Greenville from Chicago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding a cheap flight from Chicago to Greenville

  • Looking for a cheap flight? 25% of our users found flights on this route for $154 or less one-way and $308 or less round-trip.

Prefer to fly non-stop from Chicago to Greenville?

Find which airlines fly direct from Chicago to Greenville, which days they fly and book direct flights.

Nonstop departures

Chicago to Greenville

Monday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

Tuesday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

Wednesday

ANA, Air Canada, Air New Zealand, +7 more

ANA, Air Canada, +8 more

Thursday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

Friday

ANA, Air Canada, Air New Zealand, +7 more

ANA, Air Canada, +8 more

Saturday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

Sunday

ANA, Air Canada, Air New Zealand, +7 more

ANA, Air Canada, +8 more

See more direct flights

Nonstop returns

Greenville to Chicago

Monday

ANA, Air Canada, Air New Zealand, +5 more

ANA, Air Canada, +6 more

Tuesday

ANA, Air Canada, Air New Zealand, +5 more

ANA, Air Canada, +6 more

Wednesday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

Thursday

ANA, Air Canada, Air New Zealand, +5 more

ANA, Air Canada, +6 more

Friday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

Saturday

ANA, Air Canada, Air New Zealand, +5 more

ANA, Air Canada, +6 more

Sunday

ANA, Air Canada, Air New Zealand, +6 more

ANA, Air Canada, +7 more

See more direct flights
See more direct flights

Top 3 airlines serving from Chicago to Greenville

 
See real verified KAYAK customer reviews for airlines flying from Chicago to Greenville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Chicago to Greenville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10673 reviews
7.4Food
8.2Boarding
7.9Comfort
8.0Entertainment
8.6Crew
Airline reviews

A regional sized plane was used for a cross country flight with no overhead bin space. I had to "pink check" my laptop and my medications. I was NOT pleased!!!!

4.0 OkayReginald, May 2024MCI - LGA
Read more about Delta reviews

A regional sized plane was used for a cross country flight with no overhead bin space. I had to "pink check" my laptop and my medications. I was NOT pleased!!!!

Absolutely nothing flight was cancelled and delayed for 2 days. Barely a heads up I want a full refund

The plane from SNA wouldn’t start after 5 tries. The team gave me an option of flying direct from LAX and giving me a Lyft ride there! Perfect!

Best airline! Always friendly and welcoming. Skyclub was great and loved the fast free wifi on board. I also love that you can pre-order your meal on the app!

Atlanta boarding crew at gate were filled with arrogance and were disrespectful. In flight crew showed indifference to the needs of passengers. This is about the flight from ATL to BDL.

Boarding was somewhat chaotic. Unable to evaluate crew or food/drink because captain kept them seated due to turbulence. Have no idea if entertainment was offered.

The gate area was incredibly short staffed, with one representative manning 4-5 flights, which caused a 3 hr delay in boarding even though the plane was all ready to leave. Other flights also were delayed because of this. The flight crew was awesome and I feel bad for the only gate worker on call, but Delta needs to hire more employees.

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

It was a good experience except when boarding a female flight attendant did not go out of her way to assist my teenage daughters in finding space for their carry-ons after their compartments were full.

On time departure, smooth trip, flight attendant told through passengers the gate we would arrive at and the gate our outbound flight was departing from. Early arrival

I’ve had a couple flights this week on United that were delayed by an hour or more

Great! The plane was decently sized and comfortable. The staff was nice and there was great in flight entertainment

Last minute gate change nearly caused us to miss our flight. Change was not announced or displayed in the main board at the old gate. Terrible communication. When we landed we had to wait 20 minutes because there was another plane at the assigned gate. Not the crew’s fault, but adding 20 minutes to a 45 minute flight sucked.

delay several times and wait extra long to board. no entertainment service because there are problem for some rows. always encounter some delays for the last flight of the day.

The flight experience was very good! Especially the United Club!

I was not able to buy food in the flight. They refer to include your Credit card in the APP, and if you are not from USA (i have a credit card form Canada) it is not possible

The flight from Ottawa to Chicago took a lot longer due to DC in Ottawa. We got to Chicago and went to our gate to catch our flight. We only had nine minutes I found that very stressful.

Good boarding. Crew started quick with drinks and food. They came around several times for trash which I really liked. Other than turbulence due to storms in the area, flight was great.

The control panel for the seat back screen did not work at all after takeoff.

Plane was so old it had cigarette butt trays in the seat

Good flights. Departure and arrivals were on time. DFW was a little problematic in that the Skytrain without prior notice bypassed the Echo terminal so that delayed my arrival at my connecting flight.

Because I can’t stand very long in one place, I was allowed to reword.

5 hour flight - full flight - not enough room to use my computer - slightly delayed - Admirals club was excellent quality food, drink made up for flight seating. No food offerred on flight, you ahd to prebook.

Excellent- plan was barely populated. I cannot remember a flight where I was able/encouraged to stretch out!

Great flight. Boarding was efficient and quick. On time departure and smooth flight. Flight arrived early at destination. Good experience.

Had technical issue which delayed the flight period. Flight crew knew there was 5 passengers that the connecting flight was within 15 minutes once at the gate. Rather than identify the 5 passengers to assure they got first. The flight attended mentioned it but didn't assist to assure passengers with connecting flights off first. This caused a hardship and our party of 3 missed the connecting flight.

I don't like that I have to pay if I want extra leg room. The seats are so expensive; I sit in normal seats and my legs and knees cramp the entire flight. I never feel comfortable on AA flights.

Flight was delayed at departure due to weather and the need for de-icing. The flight was smooth but there was a delay at arrival due to weather. We were in a hold for 20 minutes or more. The flight arrived more than 30 minutes late. Airlines have no control over the weather and I'm glad that they follow all safety procedures. Had to wait a long time for my checked luggage. Whole process was slow and the bags arrived wet due to the rain. The onboard wifi and entertainment access was spotty and the signal was dropped several times. Otherwise the crew was great and friendly. They tried to get everyone's bags stowed and seated so we could take off.

Regarding the boarding: it needs more efforts to make it more convenient

Deicing in Denver took forever and I almost missed my connection. De-ice faster! Not Americans fault.

Book cheap flights from Chicago to Greenville

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Chicago to Greenville found on KAYAK in the last 72 hours.
7/23Tue
1 stop
15h 09mORD-GSP
$96
7/23Tue
2 stops
24h 16mORD-GSP
$104
6/10Mon
1 stop
8h 52mORD-GSP
$114
5/30Thu
nonstopAmerican Airlines
1h 50mORD-GSP
$130
5/30Thu
1 stopAmerican Airlines
3h 24mORD-GSP
$138
5/30Thu
1 stopDelta
3h 56mMDW-GSP
$139
7/23Tue
1 stopDelta
4h 00mMDW-GSP
$144
5/30Thu
nonstopUnited Airlines
2h 00mORD-GSP
$165
6/24Mon
2 stopsAllegiant Air
18h 50mMDW-GSP
$172
6/10Mon
nonstopUnited Airlines
2h 00mORD-GSP
$190

Search by stops

Search by airline

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Last minute flights from Chicago to Greenville

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Chicago to Greenville that are departing in the next 10 days.
5/17Fri
multi-stopDelta
4h 09mMDW-GSP
5/21Tue
multi-stopDelta
5h 46mGSP-MDW
$548
5/17Fri
multi-stopDelta
5h 00mORD-GSP
5/21Tue
multi-stopDelta
7h 03mGSP-ORD
$548
5/17Fri
multi-stopDelta
4h 48mORD-GSP
5/19Sun
multi-stopDelta
4h 11mGSP-ORD
$568
5/20Mon
nonstopAmerican Airlines
1h 50mORD-GSP
5/21Tue
nonstopAmerican Airlines
2h 05mGSP-ORD
$620
5/20Mon
nonstopAmerican Airlines
1h 44mORD-GSP
5/21Tue
multi-stopAmerican Airlines
3h 56mGSP-ORD
$628
5/20Mon
multi-stopAmerican Airlines
3h 42mORD-GSP
5/21Tue
multi-stopAmerican Airlines
4h 56mGSP-ORD
$636
5/17Fri
multi-stopDelta
4h 24mMDW-GSP
5/23Thu
multi-stopDelta
3h 57mGSP-MDW
$639
5/17Fri
nonstopUnited Airlines
1h 58mORD-GSP
5/17Fri
nonstopUnited Airlines
2h 15mGSP-ORD
$778
5/17Fri
multi-stopUnited Airlines
7h 10mORD-GSP
5/18Sat
multi-stopUnited Airlines
19h 32mGSP-ORD
$900
5/18Sat
multi-stopWestJet
17h 28mMDW-GSP
5/21Tue
multi-stopWestJet
32h 24mGSP-MDW
$1,466

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Flights to Greenville

Destination:

Greenville (GSP)United States

Return flight deals:

Greenville - Chicago

Cabin classes:

$633
$498
$554
$273