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Find cheap flights from Detroit to South America from $106

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South America departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/29
Sat 7/6

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$586
Bogotá
Bogotá1 stop$274
Sao Paulo
Sao Paulo3 stops$660
Cartagena
Cartagena1 stop$271
Santiago
Santiago1 stop$697
Quito
Quito3 stops$467
Guayaquil
Guayaquil2 stops$327
Cali
Cali1 stop$371
Cusco
Cusco3 stops$824
Montevideo
Montevideo2 stops$913

Good to know

Low season

September

High season

December

Cheapest flight

$106
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 30% increase in price.
Flight from Detroit to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Detroit to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to Detroit with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 12% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Detroit to South America

 
Need help choosing which airline to fly with from Detroit to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10457 reviews
7.9Comfort
8.2Boarding
8.6Crew
7.4Food
8.0Entertainment
Airline reviews

Boarding was chaotic. I didn’t finish dinner because I went to bed early. Breakfast omelet was overcooked and tasteless but croissant was better than usual. Plane was dirty—crumbs in every seam and lavatory was poorly maintained (paint peeling, etc.) and toilet paper had not been refreshed before takeoff. No cubby for storage in first and seat was narrow.

4.0 OkayPatricia, May 2024DTW - CDG
Read more about Delta reviews

Boarding was chaotic. I didn’t finish dinner because I went to bed early. Breakfast omelet was overcooked and tasteless but croissant was better than usual. Plane was dirty—crumbs in every seam and lavatory was poorly maintained (paint peeling, etc.) and toilet paper had not been refreshed before takeoff. No cubby for storage in first and seat was narrow.

Wifi wasn’t working well so we couldn't view any media.

Food service was bare-bone. Better bot to have any at all rather than hand out premade coffees and cookies to random few passengers.

Crew was great. Friendly, calm, interesting, happy to be there. That makes a huge difference. Plane was very quiet. Also quite empty so I had three seats to sleep across

Had assistance at airport getting from arrivals gate to departure gate; I couldn't have managed without that extra help. Thank you Delta.

They charge me for the luggage which is was included on the ticket

More space in the cabin. The guy in front of me leaned his seat back and I felt he was sitting in my lap.

Was a great smooth flight from Detroit to San Diego.

Late flight, always blaming the flight crew, stale almonds, pushy people. Why don’t they have the people sitting in the back board first? So much easier getting through an empty plane! Duh!!

As we lined up to board they gave our plane to a flight going to Newark. So then we got delayed until they could find another plane. Flight crew was ok. I’m assuming since it’s a shorter flight they only offered water and coffee.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

Everything was as you would expect in coach - fine. Flight was close to on time.

No air in the middle rows. Had a hard time breathing. Was dying of heat.

Flight was great Customer service was questionable until we found someone at checkin to help us. One young lady took all our passports disappeared for 15 minutes, came back with nothing done, handed to someone else and left for lunch. Very complacent. Baggage was very expensive until we went to the service counter and a separate person helped us. Even with platinum status they wouldn’t allow free bags. We will continue to fly Delta as our preferred carrier but will avoid checking in with Latam. Dr. Armand Radke

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

Flight from Lima to São Paulo didn’t have USB plug to charge the cellphone.

It was a good experience, the flight was a little too long & the food was ok

the flight from Boston to Curitiba was on time actually 30 minutes earlier. latam was not able to unload the luggage for custom checkup in Sao Paulo ii took two and half hours . i missed the flight to Curitiba spend the night in hotel and then flying in the morning to Curitiba

Tough flight with turbulence… I was told by a fellow passenger that it is common. Nonetheless, very stressful. Cordial staff.

Well....let's start from the point that I had to stay in airport for 12 hours instead of 2 that was scheduled. Poor company and even worst customer service. Never again....

The flight and boarding were easy peasy. I was traveling with my 4-year-old, so a smooth boarding experience was especially appreciated. My only piece of feedback is really about where our gate was in O'Hare. They've shoved four gates into a tiny corner of the B terminal and there isn't early enough room or seating for everyone. Not United's problem, but did dent the overall experience.

We liked the fully reclinable seats. Had center seats, so it was difficult to talk to spouse. Crew was great

Aisle chair was good and liked the foot bar preventing you from putting your foot in the isle, The breakfast on this international flight to Zurich was horrible (Europeans, specially, used to good food) may make this a dealbreaker for booking with United Airlines again. I agreed with my Spanish fellow passenger.

Dinner was okay but the breakfast was not eatable on the flight San Francisco to Zurich.

There was no screens on board AND the WiFi didn’t work. My seat was broken and couldn’t recline so I couldn’t even sleep. The flight attendants didn’t offer anything to make it more comfortable. It was such an old cramped plane, when the person in front of me reclined I couldn’t even open my tray table. All the United ads talk about guaranteeing everyone gets a screen!

The Wi-Fi was unavailable on this flight for some reason.

The flight was delayed almost 2 hours. Bad customer service etc. I will never fly Luthansa. Ever!!!

On time take off…US cabins look tired and need of refresh!

Fine. Though no food or entertainment so the survey needs to be updated with those options.

Original flight delayed several times and finally canceled at 2:30 in the morning. Staff at the gate was not very helpful in resolving problems or communicating why there were delays. I spent 34 hours at the airport before I could leave, they couldn't book me on another early flight even after canceling my original flight. Next flight available after my original flight was canceled was 22 hours later. I will never fly American Airlines again.

very very tight seats unfriendly crew who do not seem to care about the comfort of their passengers and do not know how to smile poor ground staff support at LHR and PHX

The boarding process and flight were great. However, I waited about 40 minutes for my luggage. It did not come up on the designated belt. Instead, everyone’s bags were on a cart. Not sure what the issue was, but we were not informed until another passenger went looking for her bags and found them.

There were delays on both ends. It made it less than excellent. This plane was great though

AA1537 the AC was not working properly. It was very hot and uncomfortable.

So uncomfortable to sit in the tiny space on a long, international. Food was rough. Please, less white flour and processed food.

Worst experience flying American Airlines. I fly with them often, so I was super disappointed in the service I received at gate 30 in LGA on May 24, mid-day. The flight was delayed twice. I was patiently waiting in the American Airlines lounge when I received the notice on my app that the plane was boarding 45 minutes before its newly re-scheduled take off of 4 pm (from the orginal 1:45 pm then 3:00 pm). It took me 5 min to travel from the lounge to the gate and when I arrived there at 3:20 flight gate attendant told me the flight had closed and that they announced for passengers multiple times. I showed them the notification on my app and they were really rude and unempathetic. The person who rescheduled my flight at customer service wasn't any happier but was at least helpful in getting me on the next flight.

Flight was 1/2 hour delayed leaving Phoenix. Otherwise it was an average flight. Flight crew on this trip was very nice.

Our flight was delayed 2.5 hrs due to plane being too hot! After 1.5 hrs, airline decided to use another plane but had to wait for gate, baggage transfer & beverage transfer. Anyone could tell after first half hour that another plane was required and although did not affect us many would miss connecting flights at Heathrow. I have found the stewards are not the friendliest in the industry and the food is questionable, even as I like airplane food normally, the best of the 2 flights was the yogurt & granola for breakfast.

Everything was great except for the wifi was junk. Crew was super friendly and helpful

EVERYTHING WAS WONDERFUL HOSPITALITY THE HELP.THE SEATING FRIENDLY ALWAYS HAVE A GOOD RIDE NOT ONE BAD EXPERIENCE WITH THEM

This was the smoothest flight I have had in awhile. I was also offered an exit row seat for a great upgrade cost and was able to sleep almost thr whole flight due to comfort and a smooth flight. We left on time and arrived on time.

No food not even water offered unless you buy it and no usb in the seat but other than that everything was good

Because our flight from marsh Harbor to Fort Lauderdale was over three hours delayed it caused us to miss our flight in Fort Lauderdale. Because we missed that flight, it cost us nearly $100 apiece for four different travelers which totaled nearly $400. We are seeking a reimbursement for the flight that we missed in Fort Lauderdale Florida.

Flight expected to leave at 6:40 pm ended leaving at 8:00 am the following day. I slept in a cold airport. Never again Spirit for me…

Flight was cancelled just 6 days before. No more flights that day, and the following date was sold out. Had to obtain a refund and buy more expensive flights on another airline.

The flight was on time and nice as always for me with spirit but the cabin crew were not good. They left the lights on on a red eye for the entire flight.

This was the return leg of my journey with Spirit Airlines. Despite its reputation, I found no issues as it got me from point A to B safely and without delay, especially with no mechanical delays, which is fantastic in my book! The staff, from ground crew to cabin crew, were all pleasant and hassle-free. The flight was smooth from takeoff to landing. I have absolutely no complaints about this no-frills airline!

I got a one-way, last-minute nonstop flight from PDX to BWI for only $125. Yes, I got nicked $79 more for a checked suitcase and $89 more for the BIG SEAT option, but it was worth it, even with $4.50 for coffee and $10 for a snack (the latter no different than any other airline). The grand total was still less flying on any other airline.

They didn’t let me get my boarding pass through the app because I have a lap infant. The ticket said to see a gate agent but there was no gate agent available. I was supposed to go to the kiosk. Ended up missing my flight and they said that I never checked in to my flight so there was nothing that could be done. I will never fly spirit again. Not even worth the hassle and poor customer service.

Book cheap flights from Detroit to South America

Recent round-trip flight deals

8/28Wed
1 stopSpirit Airlines
8h 22mDTW-CTG
9/11Wed
2 stopsSpirit Airlines
18h 31mCTG-DTW
$271
8/21Wed
1 stopSpirit Airlines
15h 12mDTW-BOG
9/8Sun
1 stopSpirit Airlines
17h 51mBOG-DTW
$274
6/9Sun
1 stopAmerican Airlines
18h 10mDTW-BOG
6/12Wed
1 stopAmerican Airlines
22h 51mBOG-DTW
$469
6/9Sun
2 stopsAmerican Airlines
14h 20mDTW-BOG
6/12Wed
1 stopAmerican Airlines
22h 51mBOG-DTW
$474
10/23Wed
1 stopUnited Airlines
10h 40mDTW-BOG
10/30Wed
1 stopUnited Airlines
11h 15mBOG-DTW
$663
8/28Wed
1 stopUnited Airlines
12h 54mDTW-BOG
9/10Tue
1 stopUnited Airlines
14h 32mBOG-DTW
$674
10/28Mon
2 stopsLATAM Airlines
14h 17mDTW-BOG
11/4Mon
2 stopsLATAM Airlines
13h 50mBOG-DTW
$679
8/27Tue
1 stopDelta
11h 15mDTW-UIO
9/3Tue
1 stopDelta
8h 50mUIO-DTW
$721
8/28Wed
1 stopDelta
9h 36mDTW-UIO
9/6Fri
1 stopDelta
16h 48mUIO-DTW
$741
7/18Thu
1 stopLATAM Airlines
10h 40mDTW-BOG
7/30Tue
1 stopLATAM Airlines
9h 08mBOG-DTW
$824

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Recent one-way flight deals

9/18Wed
2 stopsSpirit Airlines
17h 47mDTW-CTG
$106
9/18Wed
1 stopSpirit Airlines
8h 22mDTW-CTG
$118
10/12Sat
1 stopLATAM Airlines
6h 50mDTW-CTG
$453
9/18Wed
1 stopAir Canada
21h 30mDTW-GRU
$524
9/15Sun
1 stopAir Canada
21h 30mDTW-GRU
$629
9/18Wed
3 stopsAmerican Airlines
19h 13mDTW-SSA
$641
9/18Wed
3 stopsAmerican Airlines
22h 53mDTW-SSA
$644
8/29Thu
2 stopsLATAM Airlines
26h 25mDTW-AEP
$792
9/15Sun
2 stopsUnited Airlines
18h 30mDTW-GRU
$821
6/27Thu
1 stopUnited Airlines
12h 40mDTW-GRU
$899

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Last minute flights from Detroit to South America

Last minute flight, train and bus deals

6/4Tue
multi-stop
32h 02mDTW-UIO
6/19Wed
multi-stop
14h 20mUIO-DTW
$463
6/4Tue
multi-stop
40h 32mDTW-UIO
6/19Wed
multi-stop
26h 16mUIO-DTW
$475
5/31Fri
multi-stopSpirit Airlines
20h 10mDTW-CTG
6/6Thu
multi-stopSpirit Airlines
18h 36mCTG-DTW
$509
5/31Fri
multi-stopSpirit Airlines
18h 47mDTW-CTG
6/6Thu
multi-stopSpirit Airlines
18h 44mCTG-DTW
$522
6/4Tue
multi-stopAmerican Airlines
12h 25mDTW-BOG
6/12Wed
multi-stopAmerican Airlines
15h 17mBOG-DTW
$562
6/4Tue
multi-stopAmerican Airlines
10h 47mDTW-BOG
6/12Wed
multi-stopAmerican Airlines
15h 17mBOG-DTW
$563
6/3Mon
multi-stopLATAM Airlines
15h 12mDTW-UIO
6/10Mon
multi-stopLATAM Airlines
10h 34mUIO-DTW
$1,182
6/3Mon
multi-stopLATAM Airlines
11h 25mDTW-UIO
6/10Mon
multi-stopLATAM Airlines
10h 34mUIO-DTW
$1,186
6/2Sun
multi-stopDelta
20h 00mDTW-EZE
6/8Sat
multi-stopDelta
17h 40mEZE-DTW
$2,732
5/31Fri
multi-stopDelta
17h 45mDTW-EZE
6/3Mon
multi-stopDelta
22h 07mEZE-DTW
$2,779

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Detroit - South America Flights

Departure:

Detroit (DTW)United States

Return flight deals:

South America - Detroit

Cabin classes: