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Find cheap flights from Iowa to San Diego from $76

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/8
Sat 6/15

Search hundreds of travel sites at once for deals on flights to San Diego

In the last 7 days travelers have searched 43,895,468 times on KAYAK, and here is why:

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Good to know

Low season

January

High season

July

Cheapest flight

$76
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Des Moines to San Diego

FAQs for booking flights from Iowa to San Diego

  • How does KAYAK find such low prices on flights from Iowa to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Iowa with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Iowa to San Diego?

Find which airlines fly direct from Iowa to San Diego, which days they fly and book direct flights.

Nonstop departures

Iowa to San Diego

Monday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Tuesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Wednesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Thursday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Friday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Saturday

ANA, Aer Lingus, Aeromexico, +56 more

ANA, Aer Lingus, +57 more

Sunday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

See more direct flights

Nonstop returns

San Diego to Iowa

Monday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Tuesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Wednesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Thursday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Friday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Saturday

ANA, Aer Lingus, Aeromexico, +56 more

ANA, Aer Lingus, +57 more

Sunday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

See more direct flights
See more direct flights

Book cheap flights from Iowa to San Diego

Recent round-trip flight deals

6/7Fri
nonstopAllegiant Air
3h 37mDSM-SAN
6/10Mon
nonstopAllegiant Air
3h 25mSAN-DSM
$137
6/7Fri
nonstopAllegiant Air
3h 37mDSM-SAN
6/14Fri
nonstopAllegiant Air
3h 25mSAN-DSM
$152
6/5Wed
1 stopFrontier
5h 42mCID-SAN
6/12Wed
1 stopFrontier
27h 39mSAN-CID
$155
5/29Wed
1 stopFrontier
7h 10mDSM-SAN
6/5Wed
1 stopFrontier
25h 25mSAN-DSM
$172
5/31Fri
1 stop
11h 40mDSM-SAN
6/3Mon
nonstop
3h 28mSAN-DSM
$177
7/3Wed
1 stop
6h 48mDSM-SAN
7/8Mon
nonstop
3h 26mSAN-DSM
$199
7/3Wed
1 stopAmerican Airlines
6h 29mCID-SAN
7/9Tue
1 stopAmerican Airlines
9h 19mSAN-CID
$234
7/3Wed
1 stopAmerican Airlines
6h 29mCID-SAN
7/9Tue
2 stopsAmerican Airlines
8h 47mSAN-CID
$241
5/26Sun
1 stopDelta
6h 08mCID-SAN
5/30Thu
1 stopDelta
8h 36mSAN-CID
$286
5/26Sun
2 stopsDelta
8h 38mCID-SAN
5/30Thu
1 stopDelta
7h 32mSAN-CID
$291

Search by stops

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Recent one-way flight deals

5/25Sat
1 stopFrontier
11h 16mDSM-SAN
$76
5/15Wed
1 stopFrontier
6h 50mDSM-SAN
$82
6/24Mon
nonstopAllegiant Air
3h 37mDSM-SAN
$93
6/10Mon
nonstopAllegiant Air
3h 37mDSM-SAN
$110
6/17Mon
2 stops
18h 25mDSM-SAN
$112
6/10Mon
2 stops
25h 34mDSM-SAN
$124
6/19Wed
1 stopAmerican Airlines
8h 40mDSM-SAN
$151
6/18Tue
1 stopDelta
9h 38mDSM-SAN
$152
5/28Tue
1 stopAmerican Airlines
10h 05mDSM-SAN
$171
6/22Sat
2 stopsDelta
9h 27mCID-SAN
$269

Search by stops

Search by airline

Search by price

Last minute flights from Iowa to San Diego

Last minute flight, train and bus deals

5/13Mon
multi-stopFrontier
7h 09mDSM-SAN
6/6Thu
multi-stopFrontier
21h 22mSAN-DSM
$260
5/11Sat
multi-stopFrontier
18h 20mDSM-SAN
5/14Tue
multi-stopFrontier
26h 23mSAN-DSM
$364
5/13Mon
multi-stopAmerican Airlines
6h 52mCID-SAN
7/15Mon
multi-stopAmerican Airlines
5h 52mSAN-CID
$404
5/11Sat
multi-stopDelta
8h 20mCID-SAN
5/15Wed
multi-stopDelta
8h 52mSAN-CID
$413
5/11Sat
multi-stopDelta
11h 05mCID-SAN
5/15Wed
multi-stopDelta
8h 52mSAN-CID
$418
5/13Mon
multi-stop
9h 53mDSM-SAN
6/6Thu
multi-stop
19h 51mSAN-DSM
$427
5/13Mon
multi-stop
12h 02mDSM-SAN
6/6Thu
multi-stop
19h 51mSAN-DSM
$446
5/11Sat
multi-stopAmerican Airlines
8h 26mDSM-SAN
5/14Tue
multi-stopAmerican Airlines
11h 07mSAN-DSM
$567
5/14Tue
multi-stopUnited Airlines
20h 11mCID-SAN
5/15Wed
multi-stopUnited Airlines
17h 00mSAN-CID
$604
5/14Tue
multi-stopUnited Airlines
10h 41mCID-SAN
5/15Wed
multi-stopUnited Airlines
19h 50mSAN-CID
$609

Search by stops

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Flights to San Diego

Destination:

San Diego (SAN)United States

Return flight deals:

San Diego - Iowa

Cabin classes:

$166