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TYS - STL

$64 Find cheap flights from Knoxville to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to St. Louis departing on 6/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Wed 7/10
Wed 7/17

Search hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to St. Louis, as well as popular online travel agencies
In the last 7 days travelers have searched 42,898,604 times on KAYAK, and here is why:

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Cheap flight deals from Knoxville to St. Louis (TYS-STL)

Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
5:25 am - 9:02 amTYS-STL
4h 37m1 stop
2:16 pm - 9:25 pmSTL-TYS
6h 09m1 stop
$198Delta
Find Deal
Tue, Jul 9 - Wed, Jul 10
5:25 am - 9:02 amTYS-STL
4h 37m1 stop
5:34 pm - 10:14 pmSTL-TYS
3h 40m1 stop
$213Delta
Find Deal
Tue, Jul 9 - Sat, Jul 13
10:27 pm - 8:43 amTYS-STL
11h 16m1 stop
8:57 pm - 9:36 pmSTL-TYS
23h 39m1 stop
$216Frontier
Find Deal
Tue, Jul 9 - Thu, Jul 11
5:20 am - 9:06 amTYS-STL
4h 46m1 stop
7:10 pm - 11:54 pmSTL-TYS
3h 44m1 stop
$218Delta
Find Deal
Thu, Sep 19 - Mon, Sep 23
6:11 pm - 12:03 amTYS-STL
6h 52m1 stop
9:23 am - 2:13 pmSTL-TYS
3h 50m1 stop
$233American Airlines
Find Deal
Fri, Jun 28 - Sun, Jun 30
6:30 am - 5:29 pmTYS-STL
11h 59m1 stop
6:19 pm - 3:53 pmSTL-TYS
20h 34m2 stops
Thu, Jul 18 - Sun, Jul 21
6:00 am - 12:40 pmTYS-STL
7h 40m1 stop
5:22 pm - 3:25 pmSTL-TYS
21h 03m2 stops
Fri, Jun 28 - Sun, Jun 30
5:04 pm - 9:29 pmTYS-STL
5h 25m1 stop
5:30 pm - 11:59 pmSTL-TYS
5h 29m1 stop
$358American Airlines
Find Deal
Mon, Jul 8 - Wed, Jul 10
5:50 am - 3:49 pmTYS-STL
10h 59m2 stops
5:20 pm - 10:36 pmSTL-TYS
4h 16m1 stop
$402United Airlines
Find Deal
Thu, Sep 19 - Mon, Sep 23
9:50 am - 7:37 pmTYS-STL
10h 47m2 stops
8:25 am - 2:40 pmSTL-TYS
5h 15m1 stop
$423United Airlines
Find Deal
Sat, Aug 17 - Wed, Aug 21

Flights from Knoxville to St. Louis - Travel Insights & Trends

Get data-powered insights and trends into flights from Knoxville to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to St. Louis?

The average price of all flights from Knoxville to St. Louis clicked on KAYAK for each day over the last 12 months.
If you are looking for a flight deal from Knoxville to St. Louis, look for departures on Thursdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from St. Louis, Thursday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Knoxville to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Knoxville to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Knoxville to St. Louis is April, where tickets cost $254 on average. On the other hand, the most expensive months are June and July, where the average cost of tickets is $471 and $437 respectively.

How far in advance should I book a flight from Knoxville to St. Louis?

To calculate daily average prices, KAYAK takes all prices for each day before departure over the last year for flights from Knoxville to St. Louis, removes the top 0.1% to account for outliers, and then takes the average of all the values for each month.
To get a below average price on the flight from Knoxville to St. Louis, you should book around 3 days before departure. For the absolute cheapest price, our data suggests you should book 74 days before departure.

Which airlines provide the cheapest flights from Knoxville to St. Louis?

The cheapest price for the route for each airline clicked by KAYAK users in the last 72 hours.
In the last 3 days, Frontier offered the best one-way deal for that route, at $64. KAYAK users also found Knoxville to St. Louis round-trip flights on Delta from $198 and on Frontier from $216.

Good to know

Low season

February

High season

November

Cheapest flight

$64
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Knoxville to St. Louis

When to book flights from Knoxville to St. Louis

Are your dates flexible? Find out the best times to travel from Knoxville to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to St. Louis

  • What is the cheapest flight from Knoxville to St. Louis?

    In the last 3 days, the lowest price for a flight from Knoxville to St. Louis was $64 for a one-way ticket and $198 for a round-trip.

  • Do I need a passport to fly between Knoxville and St. Louis?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Knoxville to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to St. Louis?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Knoxville and St. Louis, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to St. Louis, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to St. Louis are Delta and American Airlines. With an average price for the route of $376 and an overall rating of 8.0, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $286 and an overall rating of 7.3.

  • How does KAYAK find such low prices on flights from Knoxville to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top airlines flying from Knoxville to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10295 reviews
7.9Comfort
8.0Entertainment
8.2Boarding
8.6Crew
7.4Food
Airline reviews

3 hours late and all they have is was a $12 meal voucher. That’s not even enough to cover fast food.

2.0 MediocreCraig, Jun 2024CVG - LGA
Read more about Delta reviews

3 hours late and all they have is was a $12 meal voucher. That’s not even enough to cover fast food.

Among the poorest flights I’ve had with Delta in a while. Entertainment system failed completely on a 7.5 hr flight. Crew seemed distracted and not the normal friendly crew. Flight overbooked it seemed… very crowded.

If I can, I always fly Delta. I’ve found their service to always be reliable and pleasant.

You could have not cancelled the flight (AA, which I will be flying from now on) left for BOS despite the fictitious weather issues (that no one in my Boston family could see). You could have rebooked my direct flight to another direct flight instead of sending me though JFK, the worst US airport after O’Hara You could have rebooked me on a Main Cabin seat (like the one I paid for in my original ticket instead of putting me a the last row on JFK->BOS leg, pocketing the difference in ticket price But I do not really care whether you will ever do that in a future because in a future neither I nor anyone from my company (unless they pay out of pocket) nor an of my clients and partners (if they heed my advice) will ever be caught dead on any of Delta flights

Really bad baggage handling. Had my Rimowa bag badly damaged at the latches.

It was pretty good I was worried with the short Layover that I might not catch my connection but the gate was there

It was good until there was a 3 hour delay because there was not any pilots to fly the plane.

There was plenty of overhead room but half of the passengers were told they had to check their carryon bags. My partner and I checked in as early as possible and our seats were split across the aisle.

Friendly flight attendants. Comfort plus seats were very comfortable and had lots of leg room. 10A and 10 B.

Flew first class so everything was great. But maybe because the flights were red eye, no meals were served, just chips. I flew Alaska Air 1st class at 9PM (2 hour flight) and they served beef short rib sliders!

Paid for premium economy had no tv the whole time the crew tried to reset/reboot but would not work they said they would put a trouble ticket in for it. We had 3 seats my tv was the only one that didn't work. They cancelled our flight re worked us on another that left us at airport over night on the floor I have a ten year old and a 78 diabetic mother which also had shingles and suffers from nerve pain in legs and back. Requested wheelchair service at all airports after the re route NO wheelchair service was there to help. WORST experience we have ever had. Went to American airlines assistance it was closed. I AM FURIOUS!!! I expect some sort of compensation from this traumatic experience and no need for flying points we don't plan on using American airlines again!!!!

This is by far the worst experience I have had with American Airlines. The start of this trip was a complete disaster. I purposely planned my trip so that I would weather any delays so that I could make very important meeting at the Pentagon. My flight was cancelled because of maintenance and I was put on the first flight the next day but I was late to the meeting. After a long week at the Pentagon I just wanted to go home and my flight home which was early in the day was delayed. Eventually the flight was delayed until the next day. I was not authorized a hotel room because DCA was my point of origin. So I paid for a hotel out of pocket. The flight this morning was boarded then deplaned because the aircraft was hot. The flow of information was not happening in DCA and made it worse when the news was bad. I am going to take a break from American for my next few military flights. Hopefully whatever has been going on with American Airlines will be resolved.

We had a 2 hour delay. The seats were smaller than most other airlines. The person in front of us wanted to lay back and we had to stop her because she was pressing against my girlfriend’s legs. We had to ask her to sit up and not lay back due to the lack of room.

Everything was fine once we actually got on our flight. It was more then annoying they canceled (delayed) our flight. We lost out on a day of our trip along with money on our stay. Plus we had to book another hotel. So expensive.

This flight was canceled and delayed several times without explanation. The plane was freezing cold and no wifi for messaging. Getting off the plane was terribly unorganized and felt like it took forever….

The flight was delayed several times without explanation. The seats were terribly uncomfortable and wifi isn’t included. All these make for a less than ideal flight.

The flights was delayed by hours and it was the firmest landing I have experienced in my life. My back is still sore.

Internet service was erratic. Crew service was poor and slow. My luggage on this non-stop flight was lost and not recovered

Terrible. I didn’t fly and I had an important meeting the next day.

Equipment swap led to 2+ hour delay on international flight. And to top it off, boarding took forever.

Book cheap flights from Knoxville to St. Louis

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Knoxville to St. Louis found on KAYAK in the last 72 hours.
6/21Fri
1 stopFrontier
11h 57mTYS-STL
$64
9/21Sat
1 stopDelta
4h 46mTYS-STL
$99
7/11Thu
1 stop
11h 59mTYS-STL
$114
6/19Wed
1 stopFrontier
19h 45mTYS-STL
$124
7/11Thu
3 stops
30h 00mTYS-STL
$178
6/22Sat
1 stop
10h 58mTYS-STL
$180
6/19Wed
3 stops
35h 55mTYS-STL
$243
9/21Sat
2 stopsAmerican Airlines
8h 06mTYS-STL
$260
6/22Sat
2 stops
11h 18mTYS-STL
$284
6/21Fri
2 stops
22h 46mTYS-STL
$297

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Last minute flights from Knoxville to St. Louis

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Knoxville to St. Louis that are departing in the next 10 days.
6/13Thu
multi-stopAmerican Airlines
5h 50mTYS-STL
6/27Thu
multi-stopAmerican Airlines
6h 44mSTL-TYS
$251
6/13Thu
multi-stopAmerican Airlines
10h 18mTYS-STL
6/27Thu
multi-stopAmerican Airlines
5h 42mSTL-TYS
$523
6/13Thu
multi-stopAmerican Airlines
6h 20mTYS-STL
6/27Thu
multi-stopAmerican Airlines
7h 13mSTL-TYS
$528
6/13Thu
multi-stopAmerican Airlines
4h 10mTYS-STL
6/17Mon
multi-stopAmerican Airlines
5h 20mSTL-TYS
$555
6/13Thu
multi-stopAmerican Airlines
10h 18mTYS-STL
6/17Mon
multi-stopAmerican Airlines
25h 57mSTL-TYS
$1,116
6/13Thu
multi-stopAmerican Airlines
10h 18mTYS-STL
6/17Mon
multi-stopAmerican Airlines
13h 11mSTL-TYS
$1,146

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Knoxville - St. Louis Flights

Departure:

Knoxville (TYS)United States

Destination:

St. Louis (STL)United States

Return flight deals:

St. Louis - Knoxville

Cabin classes: