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Find cheap flights from Missouri to John Wayne (Santa Ana) from $57

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Santa Ana departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/8
Sat 6/15

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In the last 7 days travelers have searched 43,968,530 times on KAYAK, and here is why:

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Good to know

Low season

January

High season

July

Cheapest flight

$57
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from St. Louis to Santa Ana

FAQs for booking flights from Missouri to John Wayne (Santa Ana)

  • How does KAYAK find such low prices on flights from Missouri to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missouri to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Missouri with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Missouri to Santa Ana?

Find which airlines fly direct from Missouri to J. Wayne/Orange Cnty, which days they fly and book direct flights.

Nonstop departures

Missouri to Santa Ana J. Wayne/Orange Cnty

Monday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

Tuesday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

Wednesday

ANA, Aer Lingus, Aeromexico, +31 more

ANA, Aer Lingus, +32 more

Thursday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

Friday

ANA, Aer Lingus, Aeromexico, +31 more

ANA, Aer Lingus, +32 more

Saturday

ANA, Aer Lingus, Aeromexico, +33 more

ANA, Aer Lingus, +34 more

Sunday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

See more direct flights

Nonstop returns

Santa Ana J. Wayne/Orange Cnty to Missouri

Monday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

Tuesday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

Wednesday

ANA, Aer Lingus, Aeromexico, +31 more

ANA, Aer Lingus, +32 more

Thursday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

Friday

ANA, Aer Lingus, Aeromexico, +31 more

ANA, Aer Lingus, +32 more

Saturday

ANA, Aer Lingus, Aeromexico, +33 more

ANA, Aer Lingus, +34 more

Sunday

ANA, Aer Lingus, Aeromexico, +32 more

ANA, Aer Lingus, +33 more

See more direct flights
See more direct flights

Book cheap flights from Missouri to John Wayne (Santa Ana)

Recent round-trip flight deals

5/31Fri
1 stopSpirit Airlines
7h 25mSTL-SNA
6/4Tue
1 stopSpirit Airlines
21h 45mSNA-STL
$133
5/30Thu
1 stop
18h 46mSTL-SNA
6/4Tue
1 stop
21h 45mSNA-STL
$134
5/23Thu
1 stopFrontier
18h 46mSTL-SNA
5/26Sun
1 stopFrontier
12h 02mSNA-STL
$138
5/30Thu
1 stopFrontier
18h 46mSTL-SNA
6/3Mon
1 stopFrontier
6h 32mSNA-STL
$147
8/21Wed
1 stopDelta
9h 12mSGF-SNA
8/24Sat
1 stopDelta
7h 30mSNA-SGF
$266
5/23Thu
1 stopAmerican Airlines
10h 49mSGF-SNA
6/4Tue
1 stopAmerican Airlines
5h 47mSNA-SGF
$299
9/7Sat
1 stopUnited Airlines
7h 35mJLN-SNA
9/10Tue
1 stopUnited Airlines
6h 59mSNA-JLN
$321
8/21Wed
1 stopUnited Airlines
7h 00mSGF-SNA
8/24Sat
1 stopUnited Airlines
8h 56mSNA-SGF
$326
5/23Thu
1 stopAmerican Airlines
10h 49mSGF-SNA
6/4Tue
2 stopsAmerican Airlines
8h 19mSNA-SGF
$329
5/25Sat
1 stopDelta
6h 20mMCI-SNA
5/28Tue
1 stopDelta
5h 04mSNA-MCI
$393

Search by stops

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Recent one-way flight deals

6/3Mon
1 stopSpirit Airlines
7h 25mSTL-SNA
$57
5/15Wed
1 stopSpirit Airlines
24h 27mSTL-SNA
$62
5/15Wed
1 stopFrontier
26h 04mSTL-SNA
$83
5/16Thu
1 stopFrontier
18h 46mSTL-SNA
$95
6/4Tue
1 stopDelta
5h 51mMCI-SNA
$143
6/7Fri
3 stops
22h 18mSTL-SNA
$158
5/30Thu
1 stopDelta
5h 21mMCI-SNA
$163
6/6Thu
2 stops
22h 52mSTL-SNA
$182
5/29Wed
1 stopUnited Airlines
8h 32mMCI-SNA
$183
6/25Tue
1 stopUnited Airlines
8h 44mSGF-SNA
$198

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Search by price

Last minute flights from Missouri to Santa Ana

Last minute flight, train and bus deals

5/11Sat
multi-stopFrontier
6h 10mSTL-SNA
5/18Sat
multi-stopFrontier
5h 29mSNA-STL
$223
5/11Sat
multi-stopFrontier
6h 10mSTL-SNA
5/18Sat
multi-stopFrontier
5h 29mSNA-STL
$229
5/13Mon
multi-stop
22h 25mSTL-SNA
5/18Sat
multi-stop
5h 29mSNA-STL
$291
5/13Mon
multi-stop
22h 25mSTL-SNA
5/17Fri
multi-stop
6h 32mSNA-STL
$310
5/11Sat
multi-stopSpirit Airlines
5h 03mMCI-SNA
6/10Mon
multi-stopSpirit Airlines
12h 50mSNA-MCI
$426
5/10Fri
multi-stopSpirit Airlines
5h 03mMCI-SNA
6/8Sat
multi-stopSpirit Airlines
12h 50mSNA-MCI
$446
5/14Tue
multi-stopUnited Airlines
11h 08mMCI-SNA
5/15Wed
multi-stopUnited Airlines
12h 27mSNA-MCI
$589
5/14Tue
multi-stopUnited Airlines
10h 04mMCI-SNA
5/17Fri
multi-stopUnited Airlines
16h 21mSNA-MCI
$602
5/11Sat
multi-stopDelta
8h 37mSTL-SNA
5/15Wed
multi-stopDelta
9h 38mSNA-STL
$728
5/14Tue
multi-stopDelta
6h 35mSTL-SNA
5/17Fri
multi-stopDelta
7h 11mSNA-STL
$752

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Flights to John Wayne (Santa Ana)

Destination:

John Wayne (Santa Ana) (SNA)United States

Return flight deals:

John Wayne (Santa Ana) - Missouri

Cabin classes: