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Find cheap flights from Myrtle Beach to South America from $80

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to South America departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/29
Sat 7/6

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$2,138
Guayaquil
Guayaquil1 stop$359

Good to know

Low season

May

High season

June

Cheapest flight

$80
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Myrtle Beach to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to Myrtle Beach with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 9% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top airlines flying from Myrtle Beach to South America

 
Need help choosing which airline to fly with from Myrtle Beach to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10457 reviews
7.4Food
8.0Entertainment
8.2Boarding
7.9Comfort
8.6Crew
Airline reviews

I've flown many many times on Northwest and then Delta. The crew on this flight were absolutely the best I've had the pleasure of being looked after by.

10.0 ExcellentAnonymous, May 2024MSP - YVR
Read more about Delta reviews

I've flown many many times on Northwest and then Delta. The crew on this flight were absolutely the best I've had the pleasure of being looked after by.

Flew first class so everything was great. But maybe because the flights were red eye, no meals were served, just chips. I flew Alaska Air 1st class at 9PM (2 hour flight) and they served beef short rib sliders!

Had to change aircraft due to a faulty door. Surprisingly it only caused about an hour and a half of delay. Delta handled this situation as well as can be expected.

Awful. Flight was continuously getting delayed and gates kept changing without any reason. Flight was delayed for more then 3 hours

Paid premium for Delta only to be on safe but tired old 767 with ancient cabin in mediocre condition. Poor wifi and horrible inflight entertainment. Hardly a premium experience. Should have flown SW and had fun flight crew and no pretense

Our flight to Zurich was delayed by almost 3 hours, so we missed our next flight. There was no indication it would be delayed this much. We were told the gate had changed and then it apparently took over 2 hours to load the "catering" on the plane. We were not compensated in any way for the trouble.

Rated entertainment as Mediocre as there were major problems with the Infotainment system that took probably a half hour for them to fix.

Your crew could maybe answer the call bell at least one of the times I pressed it. I pressed it first time with 2.5 hours left in our flight bc my partner was hungry and wanted a sandwich. We finally got the sandwich with 40 mins left in the flight.

Half the bathrooms assigned to economy were out of action

Delta crushed it. Flight attendant in first was attentive and just never stopped. Honestly one of the best domestic flights I’ve been on.

This was the smoothest flight I have had in awhile. I was also offered an exit row seat for a great upgrade cost and was able to sleep almost thr whole flight due to comfort and a smooth flight. We left on time and arrived on time.

No food not even water offered unless you buy it and no usb in the seat but other than that everything was good

Because our flight from marsh Harbor to Fort Lauderdale was over three hours delayed it caused us to miss our flight in Fort Lauderdale. Because we missed that flight, it cost us nearly $100 apiece for four different travelers which totaled nearly $400. We are seeking a reimbursement for the flight that we missed in Fort Lauderdale Florida.

Flight expected to leave at 6:40 pm ended leaving at 8:00 am the following day. I slept in a cold airport. Never again Spirit for me…

Flight was cancelled just 6 days before. No more flights that day, and the following date was sold out. Had to obtain a refund and buy more expensive flights on another airline.

The flight was on time and nice as always for me with spirit but the cabin crew were not good. They left the lights on on a red eye for the entire flight.

This was the return leg of my journey with Spirit Airlines. Despite its reputation, I found no issues as it got me from point A to B safely and without delay, especially with no mechanical delays, which is fantastic in my book! The staff, from ground crew to cabin crew, were all pleasant and hassle-free. The flight was smooth from takeoff to landing. I have absolutely no complaints about this no-frills airline!

I got a one-way, last-minute nonstop flight from PDX to BWI for only $125. Yes, I got nicked $79 more for a checked suitcase and $89 more for the BIG SEAT option, but it was worth it, even with $4.50 for coffee and $10 for a snack (the latter no different than any other airline). The grand total was still less flying on any other airline.

It was the worst ever, i will be filing a lawsuit to get a refund. Our flight was delayed 4 hours so we would miss our connecting flight, we were not rebooked to our destination the same day, we were not offered any options to get home on the same day despite being clear that we absolutely cannot get stranded at night due to family, we were forced to book our own flights on a different airline to get home, and spririt is refusing a refund because our flight wasn't cancelled, only delayed. oh yeah, and they lost our luggage on the first part of the trip and you cannot get a hold of customer service when anything goes wrong, on hold for 30+ minutes. and their app breaks so you can't use that either.

This recognisable no-frills airline gets me from point-A to point-B. I was able to get to Chicago without stress. The checked baggage collection and reclaim could be improved.

Book cheap flights from Myrtle Beach to South America

Recent round-trip flight deals

7/24Wed
1 stopSpirit Airlines
14h 04mMYR-GYE
8/7Wed
1 stopSpirit Airlines
16h 23mGYE-MYR
$359
7/24Wed
1 stop
14h 04mMYR-GYE
8/6Tue
2 stops
16h 02mGYE-MYR
$392
7/23Tue
2 stopsSpirit Airlines
25h 42mMYR-GYE
8/7Wed
1 stopSpirit Airlines
16h 23mGYE-MYR
$398
7/23Tue
1 stopSpirit Airlines
27h 29mMYR-GYE
8/7Wed
1 stopSpirit Airlines
19h 43mGYE-MYR
$402
7/24Wed
1 stop
14h 06mMYR-GYE
8/10Sat
2 stops
15h 13mGYE-MYR
$428
7/23Tue
3 stops
34h 58mMYR-GYE
8/7Wed
2 stops
12h 42mGYE-MYR
$432
7/24Wed
1 stop
14h 06mMYR-GYE
8/9Fri
2 stops
25h 22mGYE-MYR
$433
7/23Tue
2 stops
26h 42mMYR-GYE
8/6Tue
2 stops
16h 02mGYE-MYR
$434
7/23Tue
2 stops
26h 42mMYR-GYE
8/8Thu
2 stops
12h 02mGYE-MYR
$435
9/13Fri
2 stopsDelta
18h 20mMYR-LIM
9/20Fri
2 stopsDelta
22h 20mLIM-MYR
$2,138

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Recent one-way flight deals

9/10Tue
1 stopSpirit Airlines
11h 07mMYR-MDE
$80
9/10Tue
2 stopsSpirit Airlines
12h 44mMYR-MDE
$98
9/9Mon
1 stopSpirit Airlines
11h 07mMYR-MDE
$101
9/11Wed
2 stopsSpirit Airlines
17h 34mMYR-MDE
$105
8/2Fri
2 stops
19h 21mMYR-UIO
$223
8/2Fri
3 stops
25h 15mMYR-UIO
$326
11/26Tue
2 stopsDelta
26h 08mMYR-MDE
$413
11/25Mon
2 stopsDelta
38h 28mMYR-MDE
$427
11/24Sun
2 stopsAmerican Airlines
19h 10mMYR-MDE
$476
6/7Fri
2 stopsAmerican Airlines
24h 00mMYR-SCL
$626

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Last minute flights from Myrtle Beach to South America

Last minute flight, train and bus deals

6/3Mon
multi-stop
30h 56mMYR-SCL
6/5Wed
multi-stop
35h 46mSCL-MYR
$837
6/3Mon
multi-stop
30h 56mMYR-SCL
6/4Tue
multi-stop
41h 09mSCL-MYR
$901
6/3Mon
multi-stop
31h 49mMYR-SCL
6/5Wed
multi-stop
20h 47mSCL-MYR
$1,050
6/3Mon
multi-stop
24h 26mMYR-SCL
6/5Wed
multi-stop
24h 54mSCL-MYR
$2,428
6/3Mon
multi-stop
23h 02mMYR-SCL
6/4Tue
multi-stop
17h 26mSCL-MYR
$4,167

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Myrtle Beach - South America Flights

Departure:

Myrtle Beach (MYR)United States

Return flight deals:

South America - Myrtle Beach

Cabin classes: