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$81 Find cheap flights from Ohio to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/15
Sat 6/22

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Good to know

Low season

January

High season

July

Cheapest flight

$81
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from Detroit to Knoxville

FAQs for booking flights from Ohio to Knoxville

  • How does KAYAK find such low prices on flights from Ohio to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Ohio to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Ohio to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Ohio is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Ohio to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Ohio with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Ohio to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Ohio up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Ohio to Knoxville?

Find which airlines fly direct from Ohio to McGhee Tyson, which days they fly and book direct flights.

Nonstop departures

Ohio to Knoxville McGhee Tyson

Monday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Tuesday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Wednesday

ANA, Aer Lingus, Aeromexico, +24 more

ANA, Aer Lingus, +25 more

Thursday

ANA, Aer Lingus, Aeromexico, +26 more

ANA, Aer Lingus, +27 more

Friday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Saturday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Sunday

ANA, Aer Lingus, Aeromexico, +26 more

ANA, Aer Lingus, +27 more

See more direct flights

Nonstop returns

Knoxville McGhee Tyson to Ohio

Monday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Tuesday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Wednesday

ANA, Aer Lingus, Aeromexico, +24 more

ANA, Aer Lingus, +25 more

Thursday

ANA, Aer Lingus, Aeromexico, +26 more

ANA, Aer Lingus, +27 more

Friday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Saturday

ANA, Aer Lingus, Aeromexico, +25 more

ANA, Aer Lingus, +26 more

Sunday

ANA, Aer Lingus, Aeromexico, +26 more

ANA, Aer Lingus, +27 more

See more direct flights
See more direct flights

Book cheap flights from Ohio to Knoxville

Recent round-trip flight deals

6/11Tue
1 stopFrontier
4h 42mPIT-TYS
6/18Tue
1 stopFrontier
7h 00mTYS-PIT
$123
6/11Tue
1 stopFrontier
4h 42mPIT-TYS
6/20Thu
1 stopFrontier
5h 44mTYS-PIT
$125
6/11Tue
2 stops
18h 56mPIT-TYS
6/18Tue
1 stop
15h 34mTYS-PIT
$177
6/12Wed
1 stop
10h 56mPIT-TYS
6/19Wed
1 stop
16h 34mTYS-PIT
$185
9/11Wed
1 stopAmerican Airlines
5h 28mCAK-TYS
9/18Wed
1 stopAmerican Airlines
3h 18mTYS-CAK
$195
6/12Wed
1 stopAmerican Airlines
4h 15mCLE-TYS
6/19Wed
1 stopAmerican Airlines
4h 22mTYS-CLE
$195
8/24Sat
1 stopDelta
6h 10mCMH-TYS
8/27Tue
1 stopDelta
5h 59mTYS-CMH
$198
9/3Tue
1 stopDelta
4h 17mCLE-TYS
9/7Sat
1 stopDelta
5h 33mTYS-CLE
$198
8/31Sat
1 stopUnited Airlines
4h 16mCLE-TYS
9/4Wed
1 stopUnited Airlines
3h 49mTYS-CLE
$258
5/28Tue
1 stopUnited Airlines
4h 41mCVG-TYS
6/4Tue
1 stopUnited Airlines
5h 44mTYS-CVG
$278

Search by stops

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Search by price

Recent one-way flight deals

9/16Mon
1 stopFrontier
12h 29mDTW-TYS
$81
6/16Sun
1 stopFrontier
7h 25mPIT-TYS
$85
7/9Tue
1 stopAmerican Airlines
3h 42mPIT-TYS
$98
6/26Wed
1 stopDelta
4h 51mCLE-TYS
$99
7/3Wed
1 stopAmerican Airlines
4h 25mCAK-TYS
$104
7/9Tue
2 stops
12h 36mPIT-TYS
$115
6/29Sat
1 stopAllegiant Air
5h 23mPIT-TYS
$119
5/22Wed
1 stop
10h 25mDTW-TYS
$138
5/25Sat
1 stopAllegiant Air
7h 02mPIT-TYS
$139
6/16Sun
nonstopDelta
1h 31mDTW-TYS
$224

Search by stops

Search by airline

Search by price

Last minute flights from Ohio to Knoxville

Last minute flight, train and bus deals

5/21Tue
multi-stopFrontier
18h 38mDTW-TYS
5/28Tue
multi-stopFrontier
7h 39mTYS-DTW
$149
5/20Mon
multi-stopFrontier
11h 30mCLE-TYS
5/21Tue
multi-stopFrontier
10h 03mTYS-CLE
$183
5/17Fri
multi-stopDelta
3h 46mCMH-TYS
5/24Fri
multi-stopDelta
5h 16mTYS-CMH
$236
5/21Tue
multi-stopAmerican Airlines
5h 43mPIT-TYS
5/28Tue
multi-stopAmerican Airlines
4h 10mTYS-PIT
$250
5/18Sat
multi-stopAmerican Airlines
4h 17mPIT-TYS
5/20Mon
multi-stopAmerican Airlines
4h 07mTYS-PIT
$287
5/17Fri
multi-stopDelta
3h 57mPIT-TYS
5/20Mon
multi-stopDelta
4h 39mTYS-PIT
$288
5/20Mon
multi-stop
10h 45mDTW-TYS
6/2Sun
multi-stop
27h 54mTYS-DTW
$297
5/20Mon
multi-stop
9h 25mDTW-TYS
6/2Sun
multi-stop
16h 18mTYS-DTW
$300
5/21Tue
multi-stopUnited Airlines
14h 40mPIT-TYS
5/28Tue
multi-stopUnited Airlines
3h 50mTYS-PIT
$487
5/21Tue
multi-stopUnited Airlines
4h 02mDTW-TYS
5/26Sun
multi-stopUnited Airlines
11h 10mTYS-DTW
$662

Search by stops

Search by airline

Search by price