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Find cheap flights from South Carolina to Chicago from $42

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Chicago departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Tue 5/28
Tue 6/4

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In the last 7 days travelers have searched 43,623,357 times on KAYAK, and here is why:

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Good to know

Low season

January

High season

August

Cheapest flight

$42
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Charlotte to Chicago O'Hare Airport

FAQs for booking flights from South Carolina to Chicago

  • How does KAYAK find such low prices on flights from South Carolina to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Chicago?

Find which airlines fly direct from South Carolina to Chicago, which days they fly and book direct flights.

Nonstop departures

South Carolina to Chicago

Monday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Tuesday

ANA, Aer Lingus, Aerolineas Argentinas, +78 more

ANA, Aer Lingus, +79 more

Wednesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Thursday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Friday

ANA, Aer Lingus, Aerolineas Argentinas, +81 more

ANA, Aer Lingus, +82 more

Saturday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Sunday

ANA, Aer Lingus, Aerolineas Argentinas, +78 more

ANA, Aer Lingus, +79 more

See more direct flights

Nonstop returns

Chicago to South Carolina

Monday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Tuesday

ANA, Aer Lingus, Aerolineas Argentinas, +78 more

ANA, Aer Lingus, +79 more

Wednesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Thursday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Friday

ANA, Aer Lingus, Aerolineas Argentinas, +81 more

ANA, Aer Lingus, +82 more

Saturday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Sunday

ANA, Aer Lingus, Aerolineas Argentinas, +78 more

ANA, Aer Lingus, +79 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Chicago

Recent round-trip flight deals

5/7Tue
1 stopSpirit Airlines
11h 45mCLT-ORD
5/14Tue
1 stopSpirit Airlines
7h 46mORD-CLT
$65
5/7Tue
nonstop
2h 07mCLT-ORD
5/14Tue
1 stop
12h 18mORD-CLT
$66
6/12Wed
nonstopFrontier
2h 08mCLT-ORD
6/17Mon
nonstopFrontier
2h 00mORD-CLT
$77
6/12Wed
nonstopFrontier
2h 08mCLT-ORD
6/19Wed
nonstopFrontier
2h 00mORD-CLT
$83
6/1Sat
nonstopAmerican Airlines
2h 04mCLT-ORD
6/10Mon
nonstopAmerican Airlines
1h 57mORD-CLT
$157
5/15Wed
nonstopAmerican Airlines
2h 13mCLT-ORD
5/21Tue
nonstopAmerican Airlines
1h 59mORD-CLT
$167
7/1Mon
1 stopDelta
3h 49mCLT-MDW
7/6Sat
1 stopDelta
4h 19mMDW-CLT
$175
7/1Mon
1 stopDelta
5h 13mCLT-ORD
7/6Sat
1 stopDelta
5h 05mORD-CLT
$175
6/11Tue
nonstopUnited Airlines
2h 12mCLT-ORD
6/19Wed
nonstopUnited Airlines
2h 05mORD-CLT
$227
6/1Sat
nonstopUnited Airlines
2h 28mCHS-ORD
6/3Mon
nonstopUnited Airlines
2h 22mORD-CHS
$259

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Recent one-way flight deals

5/2Thu
nonstopFrontier
2h 07mCLT-ORD
$42
5/27Mon
nonstopSpirit Airlines
2h 15mCLT-ORD
$46
6/1Sat
nonstopAmerican Airlines
2h 04mCLT-ORD
$58
5/25Sat
nonstopAmerican Airlines
2h 09mCLT-ORD
$78
7/5Fri
1 stopDelta
3h 49mCLT-MDW
$87
6/1Sat
1 stopDelta
4h 52mCLT-ORD
$87
6/30Sun
nonstopUnited Airlines
2h 12mCLT-ORD
$98
7/26Fri
1 stopSun Country Air
23h 06mCLT-ORD
$107
6/27Thu
1 stopSun Country Air
6h 54mCLT-ORD
$109
5/29Wed
nonstopUnited Airlines
2h 37mCHS-ORD
$115

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Last minute flights from South Carolina to Chicago

Last minute flight, train and bus deals

5/2Thu
nonstopSpirit Airlines
2h 11mCLT-ORD
5/9Thu
nonstopSpirit Airlines
2h 01mORD-CLT
$93
4/30Tue
nonstopFrontier
2h 07mCLT-ORD
5/7Tue
nonstopFrontier
1h 57mORD-CLT
$119
4/30Tue
nonstop
2h 07mCLT-ORD
5/7Tue
multi-stop
10h 55mORD-CLT
$124
5/1Wed
multi-stop
6h 24mCLT-ORD
5/6Mon
multi-stop
11h 11mORD-CLT
$207
5/1Wed
nonstopAmerican Airlines
2h 08mCLT-ORD
6/3Mon
nonstopAmerican Airlines
1h 58mORD-CLT
$233
4/30Tue
multi-stopDelta
3h 50mCLT-MDW
5/7Tue
multi-stopDelta
5h 27mMDW-CLT
$242
5/3Fri
multi-stopDelta
4h 21mCLT-ORD
5/4Sat
multi-stopDelta
4h 56mORD-CLT
$252
5/1Wed
nonstopAmerican Airlines
2h 08mCLT-ORD
5/6Mon
nonstopAmerican Airlines
2h 00mORD-CLT
$273
5/3Fri
nonstopUnited Airlines
2h 12mCLT-ORD
5/4Sat
nonstopUnited Airlines
2h 09mORD-CLT
$295
5/3Fri
nonstopUnited Airlines
2h 12mCLT-ORD
5/4Sat
multi-stopUnited Airlines
4h 30mORD-CLT
$304

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Flights to Chicago

Return flight deals:

Chicago - South Carolina

Cabin classes:

$423
$871
$559
$92